The entire Eastern coast of the United States has been ravaged by the Agent X virus, wiping out all signs of hope, faith or rational thought. Off this desolate coast is a refitted nuclear sub, commandeered by a crew of survivors - including Sal DeLuca, who lost his father during their flight from Agent X. When he leads a team to scavenge for food and supplies on land, he comes across a squad of seemingly welcoming mercenaries. But he's about to find himself trapped between new terrors on the surface and mutiny below.